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CD16 Molecule (CD16) antibody (PE)

Details for Product No. ABIN135756, Supplier: Log in to see
Antigen
  • Fcgr3
  • Fcgr3a
  • CD16
  • FCGR3
  • FCGR3@
  • CD16b
  • FCG3
  • FCR-10
  • FCRIII
  • FCRIIIb
  • FcRIII
  • Fc fragment of IgG, low affinity IIa, receptor
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc receptor, IgG, low affinity III
  • Fc-gamma RIII
  • Fcgr2a
  • FCGR3A
  • FCGR3B
  • Fcgr3
  • FCGR3
Alternatives
anti-Human CD16 Molecule antibody for Flow Cytometry
Reactivity
Human
401
51
22
22
14
12
7
6
5
5
4
4
4
4
2
Host
Mouse
396
34
29
1
Clonality (Clone)
Monoclonal ()
Conjugate
PE
74
63
44
19
10
7
7
6
5
4
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
408
97
64
50
48
38
38
23
14
10
6
5
5
4
4
4
2
2
2
1
1
1
1
Options
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Clone GRM1
Isotype IgG2a
Characteristics The antibody detects: Human CD16/FcRIII
Alternative Name CD16 (CD16 Antibody Abstract)
Background CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze!
Protect conjugated products from light.

Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Takai, Li, Sylvestre, Clynes, Ravetch: "FcR gamma chain deletion results in pleiotrophic effector cell defects." in: Cell, Vol. 76, Issue 3, pp. 519-29, 1994 (PubMed).