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CD16 Molecule (CD16) antibody (SPRD)

Details for Product No. ABIN135757, Supplier: Log in to see
Antigen
  • Fcgr3
  • Fcgr3a
  • CD16
  • FCGR3
  • FCGR3@
  • CD16b
  • FCG3
  • FCR-10
  • FCRIII
  • FCRIIIb
  • FcRIII
Reactivity
Human
396
46
24
21
13
9
8
6
6
4
4
4
4
2
2
2
1
Host
Mouse
405
43
28
1
Clonality (Clone)
Monoclonal ()
Conjugate
SPRD
73
63
45
18
9
8
7
7
5
5
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
403
97
64
54
51
42
40
22
17
10
9
6
2
1
1
1
1
1
1
Supplier
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Brand Spectral Red ™
Clone GRM1
Isotype IgG2a
Characteristics The antibody detects: Human CD16/FcRIII
Alternative Name CD16 (CD16 Antibody Abstract)
Background CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze!
Protect conjugated products from light.

Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Takai, Li, Sylvestre et al.: "FcR gamma chain deletion results in pleiotrophic effector cell defects." in: Cell, Vol. 76, Issue 3, pp. 519-29, 1994 (PubMed).