IL-12p35+p70 antibody
Reactivity: Human
ELISA, Func
Host: Mouse
Monoclonal
B-T21
unconjugated
(1 reference)-
- Target
- IL-12p35+p70
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- ELISA, Functional Studies (Func)
- Specificity
- Recognises both natural and recombinant human IL-12 p35 + p70
- Purification
- Ion exchange chromatography
- Sterility
- 0.22 μm filtered
- Immunogen
- Recombinant human IL-12,Myeloma X63/AG.8653 x Balb/c spleen cells
- Clone
- B-T21
- Isotype
- IgG1 kappa
- Biological Activity Comment
- Inhibits IL-12 induced IFNg synthesis on PHA activated lymphocytes
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- Preservative
- Without preservative
- Storage
- 4 °C
- Storage Comment
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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-
: "Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation" in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5233-43, (2003) (PubMed).
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: "Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation" in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5233-43, (2003) (PubMed).
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- Target
- IL-12p35+p70
- Background
- IL-12p35/p70
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