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WWC1 antibody (AA 351-450)

WWC1 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387477
  • Target See all WWC1 Antibodies
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 36
    • 19
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 34
    • 3
    Rabbit
    Clonality
    • 34
    • 3
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWC1 antibody is un-conjugated
    Application
    • 37
    • 16
    • 12
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KIBRA
    Isotype
    IgG
    Top Product
    Discover our top product WWC1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Alternative Name
    KIBRA (WWC1 Products)
    Synonyms
    CG12600 antibody, CG33967 antibody, CG7552 antibody, Dmel\\CG33967 antibody, Kibra antibody, ORE-2 antibody, RE26350 antibody, kib antibody, l(3)02404 antibody, l(3)j5C3 antibody, l(3)neo42 antibody, HBEBP3 antibody, HBEBP36 antibody, KIBRA antibody, AA408228 antibody, AU017197 antibody, BC037006 antibody, mKIAA0869 antibody, CG33967 gene product from transcript CG33967-RB antibody, WW and C2 domain containing 1 antibody, WW, C2 and coiled-coil domain containing 1 antibody, kibra antibody, WWC1 antibody, Wwc1 antibody
    Background

    Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869

    Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

    Gene ID
    23286
    UniProt
    Q8IX03
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