CRSP Complex (AA 30-65) antibody
-
- Target
- CRSP Complex
- Binding Specificity
- AA 30-65
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CRSP complex subunit 7/ARC70
- Isotype
- IgG
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- CRSP Complex
- Background
-
Synonyms: CRSP7, CRSP70, Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70 kDa component, ARC70, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26, Transcriptional coactivator CRSP70, MED26
Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
- Gene ID
- 9441
- UniProt
- O95402
-
