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TSKU antibody (AA 231-300)

TSKU Reactivity: Human IF (cc), IF (p), ELISA, ICC, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387793
  • Target See all TSKU Antibodies
    TSKU (Tsukushin (TSKU))
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 231-300
    Reactivity
    • 22
    • 2
    Human
    Host
    • 20
    • 3
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSKU antibody is un-conjugated
    Application
    • 12
    • 12
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Tsukushin/LRRC54
    Isotype
    IgG
    Top Product
    Discover our top product TSKU Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TSKU (Tsukushin (TSKU))
    Alternative Name
    TSK/Tsukushin/LRRC54 (TSKU Products)
    Synonyms
    LRRC54 antibody, tsk antibody, tsku antibody, X-TSK antibody, e2ig4 antibody, lrrc54 antibody, tsukushi antibody, x-tsk-b1 antibody, tsukushin antibody, x-tsk-b2 antibody, c-tsk antibody, 9530051K01Rik antibody, E2ig4 antibody, Lrrc54 antibody, Tsk antibody, C-TSK antibody, C-TSKB antibody, EIIH antibody, fd51d02 antibody, wu:fd51d02 antibody, zgc:56201 antibody, E2IG4 antibody, TSK antibody, Eiih antibody, tsukushi, small leucine rich proteoglycan antibody, tsukushi, small leucine rich proteoglycan L homeolog antibody, tsukushi, small leucine rich proteoglycan S homeolog antibody, tsukushi small leucine rich proteoglycan homolog (Xenopus laevis) antibody, TSKU antibody, tsku.L antibody, tsku.S antibody, tsku antibody, Tsku antibody
    Background

    Synonyms: E2 induced gene 4 protein, E2IG4, Leucine rich repeat containing protein 54, LRRC54, TSK, Tsukushi, TSK_HUMAN, TSKU.

    Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    Gene ID
    25987
    UniProt
    Q8WUA8
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