FAM84A antibody (AA 151-250) (Alexa Fluor 350)

Catalog No. ABIN1388745

Product Details anti-FAM84A Antibody (Alexa Fluor 350)

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Binding Specificity: AA 151-250

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM84A antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NSE1/FAM84A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM84A

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Alternative Name: Nse1/Fam84a (FAM84A Products)

Synonyms: 2310003N02Rik antibody, 4731402F03Rik antibody, AW125753 antibody, Nse1 antibody, NSE1 antibody, PP11517 antibody, RGD1305779 antibody, zgc:63724 antibody, family with sequence similarity 84, member A antibody, family with sequence similarity 84 member A antibody, Fam84a antibody, FAM84A antibody, fam84a antibody

Background:

Synonyms: FAM 84A, Family with sequence similarity 84 member A, family with sequence similarity 84, member A, FLJ35392, Neurologic sensory protein 1, Neurological/sensory 1, NSE 1, NSE1, PP11517, Protein FAM84A, Protein NSE1.

Background: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44 % amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

Gene ID: 3859