DLGAP1 antibody (AA 241-360) (Alexa Fluor 555)

Catalog No. ABIN1395383

Product Details anti-DLGAP1 Antibody (Alexa Fluor 555)

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Binding Specificity: AA 241-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLGAP1 antibody is conjugated to Alexa Fluor 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DLGAP1

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Alternative Name: SAPAP1/DLGAP1 (DLGAP1 Products)

Synonyms: DKFZp469D0713 antibody, gkap antibody, sapap1 antibody, DAP-1 antibody, DAP-1-ALPHA antibody, DAP-1-BETA antibody, GKAP antibody, SAPAP1 antibody, hGKAP antibody, 4933422O14Rik antibody, 9630002F18 antibody, AI845682 antibody, AI848168 antibody, BB075781 antibody, D17Bwg0511e antibody, GKAP/SAPAP antibody, GKPA/SAPAP antibody, Gkap antibody, Sapap1 antibody, mKIAA4162 antibody, DLG associated protein 1 antibody, discs, large (Drosophila) homolog-associated protein 1 antibody, disks large-associated protein 1 antibody, discs, large homolog-associated protein 1 antibody, discs, large (Drosophila) homolog-associated protein 1b antibody, DLGAP1 antibody, LOC100408093 antibody, LOC100548434 antibody, dlgap1 antibody, Dlgap1 antibody, dlgap1b antibody

Background:

Synonyms: PSD95 binding protein 1, DAP 1 ALPHA, DAP 1, DAP 1 BETA, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, Discs large Drosophila homolog associated protein 1, Discs large homolog associated protein 1, Disks large associated protein 1, Disks large associated protein 1, alpha isoform, included, Disks large associated protein 1, beta isoform, included, Disks large-associated protein 1, DLGAP 1, Dlgap1, DLGP1_HUMAN, GKAP, GKAP/SAPAP, GKPA/SAPAP, Guanylate kinase associated protein, Guanylate kinase-associated protein, hGKAP, KIAA4162, MGC88156, mKIAA4162, PSD 95/SAP90 binding protein 1, PSD-95/SAP90-binding protein 1, SAP90/PSD 95 associated protein 1, SAP90/PSD-95-associated protein 1, SAPAP 1, SAPAP1.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.