GIPC2 antibody (AA 201-300) (Alexa Fluor 647)

Catalog No. ABIN1399884

Product Details anti-GIPC2 Antibody (Alexa Fluor 647)

Target: GIPC2 (GIPC PDZ Domain Containing Family, Member 2 (GIPC2))

Binding Specificity: AA 201-300

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIPC2 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIPC2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GIPC2

Target: GIPC2 (GIPC PDZ Domain Containing Family, Member 2 (GIPC2))

Alternative Name: GIPC-2 (GIPC2 Products)

Synonyms: SEMCAP-2 antibody, SEMCAP2 antibody, 2200002N01Rik antibody, AU021850 antibody, Semcap2 antibody, gipc1 antibody, rgs19ip1 antibody, zgc:56157 antibody, zgc:77689 antibody, gipc antibody, MGC85196 antibody, GIPC2 antibody, GIPC PDZ domain containing family member 2 antibody, GIPC PDZ domain containing family, member 2 antibody, GIPC PDZ domain containing family member 2 S homeolog antibody, GIPC2 antibody, Gipc2 antibody, gipc2 antibody, gipc2.S antibody

Background:

Synonyms: GIPC 2, GIPC-2 GIPC PDZ domain containing family, member 2, GIPC2, GIPC2_HUMAN, Likely ortholog of mouse semaF cytoplasmic domain associated protein 2, PDZ domain protein GIPC2, PDZ domain-containing protein GIPC2, SemaF cytoplasmic domain associated protein 2, Semaphorin cytoplasmic domain associated protein 2, SEMCAP 2, SEMCAP2.

Background: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.