FAM62B antibody (AA 801-921) (Cy5.5)

Catalog No. ABIN1406597

Product Details anti-FAM62B Antibody (Cy5.5)

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Binding Specificity: AA 801-921

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM62B antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ESYT2/FAM62B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM62B

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Alternative Name: ESYT2/FAM62B (ESYT2 Products)

Synonyms: CHR2SYT antibody, E-Syt2 antibody, FAM62B antibody, 2410017M09Rik antibody, 4921504I16Rik antibody, D12Ertd551e antibody, Fam62b antibody, extended synaptotagmin 2 antibody, extended synaptotagmin-like protein 2 antibody, ESYT2 antibody, Esyt2 antibody

Background:

Synonyms: Chr2 synaptotagmin, CHR2SYT, E Syt2, ESYT 2, ESYT2, Extended synaptotagmin 2, Extended synaptotagmin like protein 2, FAM 62B antibody Family with sequence similarity 62 C2 domain containing member B, Family with sequence similarity 62 member B, KIAA1228, Protein FAM62B, ESYT2_HUMAN.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM62A gene product has been provisionally designated FAM62A pending further characterization.