DNAI1/2 (AA 601-699) antibody (Cy5)
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- Target
- DNAI1/2
- Binding Specificity
- AA 601-699
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DNAI1/2
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DNAI1/2
- Background
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Synonyms: DNAI1, Axonemal dynein intermediate chain 1, Axonemal dynein intermediate chain 2, CILD 1, CILD1, DNAI 1, DNAI 2, DNAI1_HUMAN, Dynein axonemal intermediate chain 1, Dynein axonemal intermediate polypeptide 1, Dynein axonemal intermediate polypeptide 2, Dynein intermediate chain 1 axonemal, Dynein intermediate chain 1 cytosolic, Dynein intermediate chain 1, axonemal, Dynein intermediate chain 2 axonemal, Dynein intermediate chain 2 cytosolic, Dynein intermediate chain DNAI1, ICS, MGC26204, PCD.
Background: The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].
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