ZNF426 antibody (AA 421-520) (HRP)

Catalog No. ABIN1413752

Product Details anti-ZNF426 Antibody (HRP)

Target: ZNF426 (Zinc Finger Protein 426 (ZNF426))

Binding Specificity: AA 421-520

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF426 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF426

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZNF426

Target: ZNF426 (Zinc Finger Protein 426 (ZNF426))

Alternative Name: ZNF426 (ZNF426 Products)

Synonyms: ZNF426 antibody, Znf426 antibody, MGC156802 antibody, 2900057C04Rik antibody, KRAB1 antibody, Zfo61 antibody, Zfp68-rs1 antibody, mKIAA4237 antibody, zinc finger protein 426 antibody, ZNF426 antibody, Zfp426 antibody

Background:

Synonyms: HGNC:20725, MGC2663, zinc finger protein 426, ZN426_HUMAN, Znf426.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. Localized to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription.