SETBP1 antibody (AA 501-600) (HRP)

Catalog No. ABIN1414983

Product Details anti-SETBP1 Antibody (HRP)

Target: SETBP1 (SET Binding Protein 1 (SETBP1))

Binding Specificity: AA 501-600

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETBP1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SETBP1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SETBP1

Target: SETBP1 (SET Binding Protein 1 (SETBP1))

Alternative Name: SETBP1 (SETBP1 Products)

Synonyms: SEB antibody, C130092E12 antibody, Seb antibody, mKIAA0437 antibody, NI36_04265 antibody, SET binding protein 1 antibody, SET-binding protein antibody, enterotoxin antibody, SETBP1 antibody, Setbp1 antibody, setbp1 antibody, LOC100080512 antibody, NI36_RS04255 antibody

Background:

Synonyms: SEB, MRD29, SET-binding protein, SETBP1, KIAA0437

Background: SETBP1 (SET binding protein 1), also known as SEB, is a 1,542 amino acid nuclear protein that contains three AT hook DNA-binding domains, one SKI homology region and a C-terminal SET-binding domain, which is followed by three PPLPPPPP repeats. SETBP1 may be involved in SET-related tumorigenesis and leukemogenesis by regulating the transforming activity of SKI in the nucleus or suppressing SET function. As a widely expressed protein, SETBP1 is encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

Gene ID: 26040

UniProt: Q9Y6X0