Neu3 antibody

Catalog No. ABIN1449196

This Mouse Monoclonal antibody specifically detects Neu3 in WB. It exhibits reactivity toward Human.

Quick Overview for Neu3 antibody (ABIN1449196)

Target: Neu3 (Sialidase 3 (Membrane Sialidase) (Neu3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neu3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 11B

Product Details anti-Neu3 Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogen: Human NEU3 transfected COS cells

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store (in aliqouts) at -20 °C.

Target Details for Neu3

Target: Neu3 (Sialidase 3 (Membrane Sialidase) (Neu3))

Alternative Name: Sialidase-3

Background: Gangliosides, sialic acid-containing glycosphingolipids, are present in surface membranes of cells and play important functional roles in regulating a wide range of biological processes including cell surface interactions, cell differentiation, and transmembrane signaling. Plasma membrane-associated ganglioside sialidase (NEU3) has been suggested to play essential roles in regulation of cell surface functions because of its major localization in the plasma membrane and strict substrate preference for gangliosides, thought to play important roles in cell surface events through modulation of gangliosides.Synonyms: Ganglioside sialidase, Membrane sialidase, N-acetyl-alpha-neuraminidase 3, NEU3

Molecular Weight: 48 kDa

Gene ID: 9606

UniProt: Q9UQ49