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UHRF1 Binding Protein 1-Like (UHRF1BP1L) (Middle Region) antibody

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Synonyms MGC80013, UHRF1BP1L, si:dkeyp-90a8.1, 2010319N22Rik, 4930506D01Rik, AA589495, C80672, E030041M21Rik, mKIAA0701, SHIP164
Middle Region
(16), (11), (7), (3), (2), (2), (2), (1)
Human, Mouse (Murine)
(25), (2)
(22), (3)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(23), (16), (1)
Pubmed 4 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen 17 amino acid synthetic peptide near the center of Human UHRF1BP1L
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity chromatography purified via peptide column
Alternative Name UHRF1BP1L
Background The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.Synonyms: KIAA0701, UHRF1-binding protein 1-like
Gene ID 23074
NCBI Accession NP_055869
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-UHRF1 Binding Protein 1-Like (UHRF1BP1L) (Middle Region) antibody (ABIN1450050) Immunohistochemistry of UHRF1BP1L in human kidney tissue with UHRF1BP1L antibody at 2...
Western Blotting (WB) image for anti-UHRF1 Binding Protein 1-Like (UHRF1BP1L) (Middle Region) antibody (ABIN1450050) Western blot analysis of UHRF1BP1L in mouse brain tissue lysate with UHRF1BP1L antibo...
Product cited in: Karagianni, Amazit, Qin et al.: "ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 705-17, 2008 (PubMed).

Background publications Fang, Xing, Bronner et al.: "ICBP90 mediates the ERK1/2 signaling to regulate the proliferation of Jurkat T cells." in: Cellular immunology, Vol. 257, Issue 1-2, pp. 80-7, 2009 (PubMed).

Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, 2004 (PubMed).

Hopfner, Mousli, Jeltsch et al.: "ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression." in: Cancer research, Vol. 60, Issue 1, pp. 121-8, 2000 (PubMed).

Catalog No. ABIN1450050
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