UHRF1BP1L antibody (AA 980-1030)

Catalog No. ABIN6991575

Product Details anti-UHRF1BP1L Antibody

Target: UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))

Binding Specificity: AA 980-1030

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF1BP1L antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: At least two isoforms of UHRF1BP1L are known to exist, this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1

Purification: UHRF1BP1L Antibody is affinity chromatography purified via peptide column.

Immunogen: UHRF1BP1L antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1L. The immunogen is located within amino acids 980 - 1030 of UHRF1BP1L.

Isotype: IgG

Application Details

Application Notes: UHRF1BP1L antibody can be used for detection of UHRF1BP1L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: UHRF1BP1L Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: UHRF1BP1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UHRF1BP1L

Target: UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))

Alternative Name: UHRF1BP1L (UHRF1BP1L Products)

Synonyms: SHIP164 antibody, 2010319N22Rik antibody, 4930506D01Rik antibody, AA589495 antibody, C80672 antibody, E030041M21Rik antibody, mKIAA0701 antibody, MGC80013 antibody, UHRF1BP1L antibody, si:dkeyp-90a8.1 antibody, UHRF1 binding protein 1 like antibody, UHRF1 (ICBP90) binding protein 1-like antibody, UHRF1 binding protein 1-like antibody, UHRF1 binding protein 1-like L homeolog antibody, UHRF1BP1L antibody, Uhrf1bp1l antibody, uhrf1bp1l.L antibody, uhrf1bp1l antibody

Background: UHRF1BP1L Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.

Gene ID: 23074

NCBI Accession: NP_055869

UniProt: A0JNW5