RRM1 antibody (AA 246-792)

Catalog No. ABIN1500769

Product Details anti-RRM1 Antibody

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Binding Specificity: AA 246-792

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Human RRM1

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Rat (97%) Bovine (95%) Chicken (92%).

Purification: Immunoaffinity purified

Immunogen: Recombinant fragment corresponding to a region within amino acids 246 and 792 of RRM1 (SwissProt P23921). Percent identity by BLAST analysis: Human (100%), Mouse, Rat (97%), Bovine (95%), Chicken (92%).

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (1:100 - 1:1000), WB (1:500 - 1:3000)

Usage: Suggested starting dilutions are as follows: Western blot: 1:500-1:3000, IHC-Paraffin: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10 mM Citrate buffer (  pH 6.0) or Tris-EDTA buffer (  pH 8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7, 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: R1 / RRM1 (RRM1 Products)

Synonyms: CG5371 antibody, DmRNR1 antibody, Dmel\\CG5371 antibody, RNR1 antibody, RnrM1 antibody, RntL antibody, l(2)k06709 antibody, XRRM1 antibody, R1 antibody, RIR1 antibody, RR1 antibody, CHUNP6866 antibody, cb396 antibody, cb838 antibody, r1 antibody, sb:cb548 antibody, wu:fb39b07 antibody, wu:fi14b02 antibody, wu:fk95f07 antibody, ribonucleotide reductase catalytic subunit M1 antibody, Ribonucleoside diphosphate reductase large subunit antibody, ribonucleoside-diphosphate reductase large subunit antibody, ribonucleotide reductase M1 L homeolog antibody, ribonucleotide reductase M1 antibody, ribonucleotide reductase M1 polypeptide antibody, RRM1 antibody, RnrL antibody, LOC100472317 antibody, rrm1 antibody, rrm1.L antibody, Rrm1 antibody

Background: Name/Gene ID: RRM1

Synonyms: RRM1, R1, Ribonucleotide reductase M1, RR1, RIR1

Gene ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity