RNF128 antibody (AA 115-143)

Catalog No. ABIN1537774

Product Details anti-RNF128 Antibody

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Binding Specificity: AA 115-143

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF128 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF128 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128.

Clone: RB40302

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RNF128 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for RNF128

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Alternative Name: RNF128 (RNF128 Products)

Synonyms: rnf128 antibody, wu:fb57h05 antibody, zgc:77843 antibody, 1300002C13Rik antibody, AI987883 antibody, GRAIL antibody, Greul1 antibody, RGD1566282 antibody, grail antibody, greul1 antibody, ring finger protein 128a antibody, ring finger protein 128, E3 ubiquitin protein ligase antibody, ring finger protein 128 antibody, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antibody, rnf128a antibody, RNF128 antibody, Rnf128 antibody, rnf128.L antibody

Background: The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight: 46521

Gene ID: 79589

NCBI Accession: NP_078815, NP_919445

UniProt: Q8TEB7