Myotilin antibody (AA 127-155)

Catalog No. ABIN1537809

Product Details anti-Myotilin Antibody

Target: Myotilin (MYOT)

Binding Specificity: AA 127-155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myotilin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of human MYOT.

Clone: RB36975

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MYOT Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Myotilin

Target: Myotilin (MYOT)

Alternative Name: MYOT (MYOT Products)

Synonyms: LGMD1 antibody, LGMD1A antibody, MFM3 antibody, TTID antibody, TTOD antibody, 5530402I04Rik antibody, Ttid antibody, MYOT antibody, ttid antibody, myotilin antibody, MYOT antibody, Myot antibody, myot antibody

Background: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Molecular Weight: 55395

Gene ID: 9499

NCBI Accession: NP_001129412, NP_006781

UniProt: Q9UBF9