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FASL antibody

FASL Reactivity: Human WB, IP, IHC (p), IHC (fro) Host: Mouse Monoclonal I-6060 unconjugated
Catalog No. ABIN155064
  • Target See all FASL Antibodies
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Reactivity
    • 98
    • 47
    • 34
    • 18
    • 6
    • 5
    • 3
    • 2
    • 1
    Human
    Host
    • 69
    • 28
    • 10
    • 5
    • 4
    • 1
    Mouse
    Clonality
    • 76
    • 41
    Monoclonal
    Conjugate
    • 67
    • 12
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FASL antibody is un-conjugated
    Application
    • 79
    • 53
    • 26
    • 23
    • 21
    • 17
    • 13
    • 13
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody detects Fas Ligand.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Characteristics
    Synonyms: FASLG, APT1LG1, FASL, TNFSF6, CD95L protein, APTL, Tumor necrosis factor ligandsuperfamily member 6, Fas antigen ligand, Apoptosis antigen ligand
    Purification
    Affiniry Chromatography on Protein G
    Immunogen
    Recombinant Human Fas Ligand.
    Clone
    I-6060
    Isotype
    IgG1
    Top Product
    Discover our top product FASL Primary Antibody
  • Application Notes
    Western Blot (1-4 μg/mL): HeLa cell lysate can be used as a Positive Control and a 40 kDaband should be detected. Immunoprecipitation. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS, pH 7.2, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Alternative Name
    CD178 / Fas Ligand (FASL Products)
    Synonyms
    ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
    Background
    Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when crosslinked with agonistic anti-Fas antibodies or Fas ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in various tissue and cells. Both Fas and FasL are thought to play an important role in the apoptosis processes that takes place during T cell development.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
    Gene ID
    356
    UniProt
    P48023
    Pathways
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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