TAB1 antibody (C-Term)

Catalog No. ABIN155137

This Rabbit Polyclonal antibody specifically detects TAB1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TAB1 antibody (C-Term) (ABIN155137)

Target: TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAB1 Antibody

Binding Specificity: C-Term

Specificity: The antibody recognizes TAB1.

Purification: Peptide affinity purified

Immunogen: Synthetic peptide mapping to the C-terminus of human TAB1.

Application Details

Application Notes: Western Blot: 1-4 μg/mL, BaF3 cells can be used as positive controls, A approx. 60 kDa bandshould be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for TAB1

Target: TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))

Alternative Name: TAB1 / MAP3K7IP1

Background: TAB1 (TAK1 binding protein 1) is an adaptor protein that can activate TAK1 in vivo through phosphorylation of TAK1, a mitogen-activated protein kinase kinase kinase. Once activated TAK1 phosphorylates MAPK kinase MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively.Synonyms: Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, TAK1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1

Gene ID: 10454

NCBI Accession: NP_006107

UniProt: Q15750

Pathways: TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades