MYSM1 antibody (C-Term)

Catalog No. ABIN3017376

The Rabbit Polyclonal anti-MYSM1 antibody is suitable to detect MYSM1 in samples from Human. It has been validated for WB.

Quick Overview for MYSM1 antibody (C-Term) (ABIN3017376)

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYSM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYSM1 Antibody

Binding Specificity: C-Term

Sequence: PLPYSQITCL VISEEISPDG SYRLPYKFEV QQMLEEPQWG LVFEKTRWII EKYRLSHSSV PMDKIFRRDS DLTCLQKLLE CMRKTLSKVT NCFMAEEFLT EIENLFLSNY KSNQENGVTE ENCTKELLM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human MYSM1 (NP_001078956.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYSM1

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Alternative Name: MYSM1

Background: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.,MYSM1,2A-DUB,2ADUB,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,MYSM1

Molecular Weight: 26 kDa/66 kDa/95 kDa

Gene ID: 114803

UniProt: Q5VVJ2

Pathways: Chromatin Binding