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MYSM1 antibody (N-Term)

MYSM1 Reactivity: Human, Mouse WB, FACS, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN953592
  • Target See all MYSM1 Antibodies
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 118-147, N-Term
    Reactivity
    • 34
    • 17
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYSM1 antibody is un-conjugated
    Application
    • 21
    • 21
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes MYSM1 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse
    Purification
    Purified through a Protein A column followed by peptide affinity purification
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 118-147aa) of human MYSM1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MYSM1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Dephoure, Zhou, Villén, Beausoleil, Bakalarski, Elledge, Gygi: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, (2008) (PubMed).

  • Target
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Alternative Name
    MYSM1 (MYSM1 Products)
    Synonyms
    2A-DUB antibody, 2ADUB antibody, RP4-592A1.1 antibody, C130067A03Rik antibody, C530050H10Rik antibody, RGD1311787 antibody, 2adub antibody, Myb like, SWIRM and MPN domains 1 antibody, myb-like, SWIRM and MPN domains 1 antibody, Myb like, SWIRM and MPN domains 1 L homeolog antibody, MYSM1 antibody, Mysm1 antibody, mysm1.L antibody
    Background
    Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Synonyms: Histone H2A deubiquitinase MYSM1, KIAA1915, Myb-like SWIRM and MPN domain-containing protein 1
    Gene ID
    114803
    NCBI Accession
    NP_001078956
    Pathways
    Chromatin Binding
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