C6orf154 antibody (AA 51-150) (HRP)

Catalog No. ABIN1712209

Product Details anti-C6orf154 Antibody (HRP)

Target: C6orf154 (Chromosome 6 Open Reading Frame 154 (C6orf154))

Binding Specificity: AA 51-150

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6orf154 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6ORF154

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C6orf154

Target: C6orf154 (Chromosome 6 Open Reading Frame 154 (C6orf154))

Alternative Name: C6ORF154 (C6orf154 Products)

Synonyms: C6orf154 antibody, LRRC73 antibody, nod3l antibody, leucine rich repeat containing 73 antibody, LRRC73 antibody, Lrrc73 antibody

Background:

Synonyms: C6orf154, LRC73_HUMAN, Chromosome 6 open reading frame 154, dJ337H4.2, FLJ44836, hypothetical protein LOC221424, MGC131686, Uncharacterized protein C6orf154.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf154 gene product has been provisionally designated C6orf154 pending further characterization.

Gene ID: 221424