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Axin antibody (C-Term)

AXIN1 Reactivity: Human, Mouse, Rat, Cow, Dog ELISA, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN1732156
  • Target See all Axin (AXIN1) Antibodies
    Axin (AXIN1) (Axin 1 (AXIN1))
    Binding Specificity
    • 15
    • 15
    • 15
    • 14
    • 11
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog
    Host
    • 115
    • 7
    • 1
    Goat
    Clonality
    • 116
    • 7
    Polyclonal
    Conjugate
    • 37
    • 11
    • 10
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Axin antibody is un-conjugated
    Application
    • 101
    • 49
    • 39
    • 39
    • 31
    • 11
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Reacts with the C-terminus part of human AXIN1
    Cross-Reactivity
    Mouse (Murine), Cow (Bovine), Dog (Canine), Rat (Rattus)
    Cross-Reactivity (Details)
    Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
    Purification
    Antigen affinity purified
    Immunogen
    Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
    Top Product
    Discover our top product AXIN1 Primary Antibody
  • Application Notes

    Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Minimize freezing and thawing.
  • Target
    Axin (AXIN1) (Axin 1 (AXIN1))
    Alternative Name
    AXIN1 (AXIN1 Products)
    Synonyms
    AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
    Background
    Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
    UniProt
    O15169
    Pathways
    WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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