SLC9A1 antibody (C-Term)
Quick Overview for SLC9A1 antibody (C-Term) (ABIN180918)
Target
See all SLC9A1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- C-Term
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Specificity
- This antibody is specific for the Na+/H+ exchanger-1 (NHE1)a membrane protein involved in pH regulation and signal transduction.
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Characteristics
- Synonyms: Sodium/hydrogen exchanger 1, APNH, APNH1, Solute carrier family 9 member 1, Na(+)/H(+)exchanger 1, Na(+)/H(+) antiporter, amiloride-sensitive
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Purification
- Affinity Chromatography on Protein A.
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Immunogen
- Maltose Binding Protein fusion protein containing the entire C-terminal hydrophilic domainof Porcine NHE1. Genename: NHE1
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Isotype
- IgG1
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Application Notes
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Western Blot (1/500): Detects a band of approximately 100 kDa in Human kidney lysates. Not Suitable for Immunohistochemistry (Paraffin/Frozen) and Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
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Alternative Name
- SLC9A1 / NHE1
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Background
- Sodium / Hydrogen Exchanger 1 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. It is a major proton extruding system driven by the inward sodium ion chemical gradient. It also plays an important role in signal transduction.Synonyms: APNH, APNH1, Na(+)/H(+) antiporter, Na(+)/H(+) exchanger 1, Sodium/hydrogen exchanger 1, Solute carrier family 9 member 1, amiloride-sensitive
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Gene ID
- 397458
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UniProt
- P48762
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Pathways
- Glycosaminoglycan Metabolic Process, Proton Transport
Target
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