Osteocalcin antibody

Catalog No. ABIN180921

Product Details anti-Osteocalcin Antibody

Target: Osteocalcin (BGLAP)

Reactivity: Human, Rat, Cow, Rabbit, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19.

Characteristics: Synonyms: Bone Gla protein, BGLAP, Gamma-carboxyglutamic acid-containing protein

Purification: Affinity Chromatography on Protein A

Immunogen: Recombinant human osteocalcin GST fusion protein.

Clone: 2H9F11F8

Isotype: IgG2a

Application Details

Application Notes: ELISA: Suitable for use in a Sandwich ELISA with ABIN180920, ABIN316665 orABIN316666.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin (BGLAP Products)

Synonyms: BGP antibody, OC antibody, OCN antibody, Bglap1 antibody, Bglap2 antibody, OG1 antibody, mOC-A antibody, Bgp antibody, Bgpr antibody, Bgpra antibody, bgp antibody, LOC792433 antibody, ocn antibody, GLA antibody, BGLAP antibody, PMF1 antibody, bone gamma-carboxyglutamate protein antibody, bone gamma carboxyglutamate protein antibody, bone gamma-carboxyglutamate protein S homeolog antibody, bone gamma-carboxyglutamate (gla) protein antibody, osteocalcin antibody, polyamine-modulated factor 1 antibody, BGLAP antibody, Bglap antibody, bglap.S antibody, bglap antibody, ocn antibody, LOC100529177 antibody, LOC100146589 antibody

Background: Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.Synonyms: BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein

Gene ID: 632

UniProt: P02818