LMX1A antibody (Middle Region)

Catalog No. ABIN182470

This Rabbit Polyclonal antibody specifically detects LMX1A in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Rabbit.

Quick Overview for LMX1A antibody (Middle Region) (ABIN182470)

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LMX1A Antibody

Binding Specificity: Middle Region

Sequence: QNQRAKMKKL ARRQQQQQQD QQNTQRLSSA QTNGGGSAGM EGIMNPYTAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LMX1A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LMX1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMX1A

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Alternative Name: LMX1A

Background: LMX1A is necessary for the expression of bone morphogenetic protein (BMP), and for the normal generation and differentiation of the dorsal-most spinal cord neurons, the dl1 interneurons
Alias Symbols: LMX1, LMX1.1
Protein Interaction Partner: LDB1, BMPR2, ISL1, LHX3, LMX1A, TCF3,
Protein Size: 382

Molecular Weight: 43 kDa

Gene ID: 4009

NCBI Accession: NM_177398, NP_796372

UniProt: Q8TE12

Pathways: Dopaminergic Neurogenesis