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Paired Box 3 (PAX3) antibody

Antigen

Paired Box 3 (PAX3)
Synonyms WS1, CDHS, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, pax3, zgc:92547, PAX3, ws1, cdhs, hup2, pax-3, xpax3, MGC89554, MGC131061, Sp, Pax-3, splotch
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Xenopus laevis
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN182574
Quantity 0.1 mg  (Variants)
Price 251.90 $   Plus shipping costs $45.00
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anti-Paired Box 3 (PAX3) antibody

Additional Information
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Alternative name PAX3
Gene ID PAX3
UniProt Q86UQ3
Immunogen The immunogen for anti-PAX3 antibody: synthetic peptide directed towards the middle region of human PAX3
Sequence KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDE GSDIDSEPDL
Cross-Reactivity Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
Format Lyophilized
Reconstitution Add 100 µl of distilled water. Final anti-PAX3 antibody concentration is 1 mg/ml.
Description PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.
Characteristics Antigen Size: 403 amino acids
Molecular Weight 45kDa

Application Details
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Application Notes WB Suggested Anti-PAX3 Antibody Titration: 2.5ug/ml
Positive Control: Human Liver.
Purification Protein A purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Organogenesis, Lineage Markers, Transcription Factors
Restrictions For Research Use only

Publications
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Product Wachtel, Dettling, Koscielniak et al.: "Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1." in: Cancer research, Vol. 64, Issue 16, pp. 5539-45, 2004 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Paired Box 3 (PAX3)", type "Antibodies"
Hosts Rabbit (36), Mouse (8), Goat (6)
Reactivities Human (44), Mouse (Murine) (29), Rat (Rattus) (29), Cow (Bovine) (5), Dog (Canine) (5), Chicken (3), Pig (Porcine) (3), Rabbit (2), Xenopus laevis (2), Cat (Feline) (1), Quail (1), Zebrafish (1)
Applications Western Blotting (WB) (25), ELISA (21), Immunofluorescence (IF) (19), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunoprecipitation (IP) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (2), FITC (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (4), C-Term (3), Internal Region (2), AA 1-215 (1)