PIAS3 antibody (C-Term)

Catalog No. ABIN182662

This Rabbit Polyclonal antibody specifically detects PIAS3 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Pig, Horse and Guinea Pig.

Quick Overview for PIAS3 antibody (C-Term) (ABIN182662)

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIAS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PIAS3 Antibody

Binding Specificity: C-Term

Purpose: PIAS3 Antibody - C-terminal region

Sequence: TSLDEQDALG HFFQYRGTPS HFLGPLAPTL GSSHCSATPA PPPGRVSSIV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIAS3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109283

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Alternative Name: PIAS3

Background:

Background Information: PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses.

Gene Name: Protein inhibitor of activated STAT, 3

Alternative Symbols: ZMIZ5

Protein Name: E3 SUMO-protein ligase PIAS3

Molecular Weight: 68 kDa

Gene ID: 10401

NCBI Accession: NP_006090

UniProt: Q9Y6X2

Pathways: JAK-STAT Signaling