SP140 antibody (N-Term)

Catalog No. ABIN182690

The Rabbit Polyclonal anti-SP140 antibody is suitable to detect SP140 in samples from Human, Mouse, Rat, Dog, Horse and Pig. It has been validated for WB and IHC.

Quick Overview for SP140 antibody (N-Term) (ABIN182690)

Target: SP140 (SP140 Nuclear Body Protein (SP140))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP140 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SP140 Antibody

Binding Specificity: N-Term

Purpose: SP140 Antibody - N-terminal region

Sequence: PEPIFRFFRE NKVEIASAIT RPFPFLMGLR DRSFISEQMY EHFQEAFRNL

Predicted Reactivity: Dog: 86%, Horse: 86%, Human: 100%, Mouse: 77%, Pig: 86%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against SP140. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SP140

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112528

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SP140

Target: SP140 (SP140 Nuclear Body Protein (SP140))

Alternative Name: SP140

Background:

Background Information: SP140 is the nuclear body protein found specifically in all NP cells. HIV-1 infection induced its partial dispersal from nuclear bodies into cytosolic colocalization with Vif.

Gene Name: SP140 nuclear body protein

Alternative Symbols: LYSP100, LYSP100-A, LYSP100-B

Protein Name: Nuclear body protein SP140

Molecular Weight: 46kDa

Gene ID: 11262

NCBI Accession: NP_001005176

UniProt: Q13342