SP140 antibody (AA 1-180)

Catalog No. ABIN7270507

This Rabbit Polyclonal antibody specifically detects SP140 in WB. It exhibits reactivity toward Human.

Quick Overview for SP140 antibody (AA 1-180) (ABIN7270507)

Target: SP140 (SP140 Nuclear Body Protein (SP140))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP140 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SP140 Antibody

Binding Specificity: AA 1-180

Purpose: SP140 Rabbit pAb

Sequence: MAQQGQQGQM ASGDSNLNFR MVAEIQNVEG QNLQEQVCPE PIFRFFRENK VEIASAITRP FPFLMGLRDR SFISEQMYEH FQEAFRNLVP VTRVMYCVLS ELEKTFGWSH LEALFSRINL MAYPDLNEIY RSFQNVCYEH SPLQMNNVND LEDRPRLLPY GKQENSNACH EMDDIAVPQE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SP140 (NP_001265380).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SP140

Target: SP140 (SP140 Nuclear Body Protein (SP140))

Alternative Name: SP140

Background: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016],LYSP100;LYSP100-A;LYSP100-B;SP140,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,SP140

Gene ID: 11262

UniProt: Q13342