T-Box 6 antibody (Middle Region)

Catalog No. ABIN182800

This Rabbit Polyclonal antibody specifically detects T-Box 6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Pig, Cow and Rabbit.It has been mentioned in 1 publication

Quick Overview for T-Box 6 antibody (Middle Region) (ABIN182800)

Target: T-Box 6 (TBX6)

Reactivity: Human, Mouse, Rat, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Box 6 Antibody

Binding Specificity: Middle Region

Purpose: TBX6 Antibody - middle region

Sequence: AKGFRENGRN CKRERDARVK RKLRGPEPAA TEAYGSGDTP GGPCDSTLGG

Predicted Reactivity: Cow: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TBX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33404-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-T-Box 6 antibody (ABIN182800)

Blin, Nury, Stefanovic, Neri, Guillevic, Brinon, Bellamy, Rücker-Martin, Barbry, Bel, Bruneval, Cowan, Pouly, Mitalipov, Gouadon, Binder, Hagège, Desnos, Renaud, Menasché, Pucéat: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).

Target Details for T-Box 6

Target: T-Box 6 (TBX6)

Alternative Name: TBX6

Background:

Background Information: TBX6 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures.

Gene Name: T-box 6

Alternative Symbols: SCDO5

Protein Name: T-box transcription factor TBX6

Molecular Weight: 47kDa

Gene ID: 6911

NCBI Accession: NP_004599

UniProt: O95947