TCEA1 antibody (N-Term)

Catalog No. ABIN182803

This Rabbit Polyclonal antibody specifically detects TCEA1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse and Rabbitand has been mentioned in 1 publication.

Quick Overview for TCEA1 antibody (N-Term) (ABIN182803)

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TCEA1 Antibody

Binding Specificity: N-Term

Sequence: KSWKKLLDGP STEKDLDEKK KEPAITSQNS PEAREESTSS GNVSNRKDET

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TCEA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCEA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 301 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TCEA1 antibody (ABIN182803)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for TCEA1

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Alternative Name: TCEA1

Background: TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
Alias Symbols: SII, TCEA, TF2S, GTF2S, TFIIS
Protein Interaction Partner: UBC, SORD, PGD, LDHA, CSE1L, BCCIP, CHORDC1, TBP, MCM5, MCM3, MCM2, GTF2H1, GTF2F1, GTF2E1, GTF2B, CDK8, MED26, POLR2C, NAA16, RBM25, SF3B2, UBAC1, POLR2A, APP, PAF1, UBR5, CDK9, LEO1, WDR61, CDC73, RTF1, CTR9, POLR2B, DDX5, INTS1, SF3B3, SNRNP200, SF3A1,
Protein Size: 301

Molecular Weight: 34 kDa

Gene ID: 6917

NCBI Accession: NM_006756, NP_006747

UniProt: P23193