Claudin 17 antibody (Middle Region)

Catalog No. ABIN182849

There is 1 publication for this product available. The Rabbit Polyclonal anti-Claudin 17 antibody is suitable to detect Claudin 17 in samples from Human, Mouse, Rat, Dog, Cow, Pig, Horse, Sheep, Guinea Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for Claudin 17 antibody (Middle Region) (ABIN182849)

Target: Claudin 17 (CLDN17)

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Sheep, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Claudin 17 Antibody

Binding Specificity: Middle Region

Purpose: CLDN17 Antibody - middle region

Sequence: KQVQCTGSNE RAKAYLLGTS GVLFILTGIF VLIPVSWTAN IIIRDFYNPA

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against CLDN17. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN17

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097501

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Claudin 17 antibody (ABIN182849)

Michlig, Damak, Le Coutre: "Claudin-based permeability barriers in taste buds." in: The Journal of comparative neurology, Vol. 502, Issue 6, pp. 1003-11, (2007) (PubMed).

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: CLDN17

Background:

Background Information: CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.

Gene Name: Claudin 17

Protein Name: Claudin-17

Molecular Weight: 25kDa

Gene ID: 26285

NCBI Accession: NP_036263

UniProt: P56750

Pathways: Cell-Cell Junction Organization, Hepatitis C