Tryptophan Hydroxylase 2 (TPH2) antibody
| Antigen |
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| Synonyms |
TPH2, NTPH, ADHD7, FLJ37295, MGC138871, MGC138872, Ntph, tph2, tph1l, tphD2, tphR, wu:fq15a04 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Dog (Canine), Mouse (Murine), Rat (Rattus), Chicken
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Application
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| Catalog no. |
ABIN182938 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Tryptophan 5-hydroxylase 2 (TPH2)
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Gene ID
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TPH2
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UniProt
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Q8IWU9
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Immunogen
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The immunogen for anti-TPH2 antibody: synthetic peptide directed towards the N terminal of human TPH2
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Sequence
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REAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHI ESRKSRRRSS
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-TPH2 antibody concentration is 1 mg/ml.
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Description
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Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
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Characteristics
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Antigen Size: 490 amino acids
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Molecular Weight
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56kDa
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Application Notes
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WB Suggested Anti-TPH2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Walther, Peter, Bashammakh et al.: "Synthesis of serotonin by a second tryptophan hydroxylase isoform." in: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, 2003 (PubMed).
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Alternatives for antigen "Tryptophan Hydroxylase 2 (TPH2)", type "Antibodies"
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Hosts
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Rabbit (38), Goat (9)
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Reactivities
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Human (36), Rat (Rattus) (30), Mouse (Murine) (29), Cow (Bovine) (22), Horse (Equine) (18), Dog (Canine) (3), Zebrafish (Danio rerio) (2), Chicken (1), Pig (Porcine) (1), Zebrafish (1)
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Applications
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Western Blotting (WB) (25), ELISA (17), Immunofluorescence (IF) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Epitopes
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AA 208-245 (18), N-Term (7), Internal Region (4), pSer19 (4), AA 16-29 (2), Center (2), Internal Region,AA 173-203 (1), N-Term,AA 16-29 (1)
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