ASH2L antibody (N-Term)

Catalog No. ABIN182955

This anti-ASH2L antibody is a Rabbit Polyclonal antibody detecting ASH2L in WB. Suitable for Human, Mouse, Rat, Dog, Horse, Cow and Guinea Pig.

Quick Overview for ASH2L antibody (N-Term) (ABIN182955)

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASH2L Antibody

Binding Specificity: N-Term

Sequence: EPSSGEAEGG EANLVDVSGG LETESSNGKD TLEGAGDTSE VMDTQAGSVD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASH2L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 628 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L

Background: ASH2L plays a role in hematopoiesis and is associated with some special kinds of leukemia. The amount of ASH2L transcripts is extremely high in fetal liver, testis, and leukemia cell lines with erythroid and megakaryocytic potential.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: CXXC1, DPY30, SETD1A, RBBP5, PPARG, KMT2A, KMT2D, UBC, SENP3, KDM6A, PPP1CC, SMAD9, KDM6B, WWP1, BRCA1, BARD1, WDR5, MEN1, USF1, KMT2C, HCFC2, SETD1B, KDM4B, KMT2B, HCFC1, ESR1, CDC73, HIST3H3, PYGO2, WDR82, PSMC5, PRMT1, E2F4, E2F1, PAGR1, NCOA6, PAXIP1,
Protein Size: 628

Molecular Weight: 69 kDa

Gene ID: 9070

NCBI Accession: NM_004674, NP_004665

UniProt: Q9UBL3