ASH2L antibody

Catalog No. ABIN7270266

Product Details anti-ASH2L Antibody

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: ASH2L Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ASH2L

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L (ASH2L Products)

Synonyms: ASH2 antibody, ASH2L1 antibody, ASH2L2 antibody, Bre2 antibody, fb34c06 antibody, fe38b04 antibody, fi20h02 antibody, wu:fb34c06 antibody, wu:fe38b04 antibody, wu:fi20h02 antibody, zgc:171444 antibody, ASH2L antibody, ash2-like antibody, ASH2 like histone lysine methyltransferase complex subunit antibody, ash2 (absent, small, or homeotic)-like (Drosophila) antibody, ash2 (absent, small, or homeotic)-like L homeolog antibody, ASH2L antibody, Ash2l antibody, ash2l antibody, ash2l.L antibody

Background: Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.,ASH2, ASH2L1, ASH2L2, Bre2,Cancer,Chromatin Remodeling,Epigenetics & Nuclear Signaling,ASH2L

Molecular Weight: 69kDa

Gene ID: 9070

UniProt: Q9UBL3