CLIC4 antibody (N-Term)

Catalog No. ABIN183143

The Rabbit Polyclonal anti-CLIC4 antibody has been validated for WB. It is suitable to detect CLIC4 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow and Zebrafish (Danio rerio).

Quick Overview for CLIC4 antibody (N-Term) (ABIN183143)

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLIC4 Antibody

Binding Specificity: N-Term

Sequence: LSMPLNGLKE EDKEPLIELF VKAGSDGESI GNCPFSQRLF MILWLKGVVF

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 253 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLIC4

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Alternative Name: CLIC4

Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 4 (CLIon Channel4) protein, encoded by the CLIon Channel4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Alias Symbols: H1, huH1, p64H1, CLIC4L, MTCLIC
Protein Interaction Partner: UBC, SUMO2, GRDX, REL, HSP90AB1, HNRNPA1, SPRTN, CDK2, DNM1, YWHAZ, ACTB,
Protein Size: 253

Molecular Weight: 28 kDa

Gene ID: 25932

NCBI Accession: NM_013943, NP_039234

UniProt: Q5VSX5