CLIC4 antibody (N-Term)

Catalog No. ABIN7184432

Product Details anti-CLIC4 Antibody

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human CLIC4.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CLIC4

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Alternative Name: CLIC4 (CLIC4 Products)

Synonyms: CLIC4L antibody, H1 antibody, MTCLIC antibody, huH1 antibody, p64H1 antibody, cb142 antibody, wu:fb33c05 antibody, wu:fc30h10 antibody, clic4 antibody, MGC89006 antibody, CLIC4 antibody, DKFZp459A0325 antibody, D0Jmb3 antibody, TU-74 antibody, mc3s5 antibody, mtCLIC antibody, xclic4 antibody, chloride intracellular channel 4 antibody, chloride intracellular channel 4 (mitochondrial) antibody, chloride intracellular channel 4 S homeolog antibody, CLIC4 antibody, Clic4 antibody, clic4 antibody, clic4.S antibody

Background:

Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

Wiemann S., Genome Res. 11:422-435(2001).
Edwards J.C., Am. J. Physiol. 276:F398-F408(1999).
Chuang J.Z., J. Neurosci. 19:2919-2928(1999).

Aliases: Chloride intracellular channel 4 antibody, Chloride intracellular channel 4 (mitochondrial) antibody, Chloride intracellular channel 4 like antibody, Chloride intracellular channel protein 4 antibody, Clic4 antibody, CLIC4_HUMAN antibody, CLIC4L antibody, DKFZP566G223 antibody, FLJ38640 antibody, H1 antibody, HUH1 antibody, Intracellular chloride ion channel protein p64H1 antibody, MC3S5 antibody, mtCLIC antibody, p64H1 antibody

UniProt: Q9Y696