HMGB3 antibody (C-Term)

Catalog No. ABIN183218

The Rabbit Polyclonal anti-HMGB3 antibody has been validated for WB. It is suitable to detect HMGB3 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig and Goat.

Quick Overview for HMGB3 antibody (C-Term) (ABIN183218)

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGB3 Antibody

Binding Specificity: C-Term

Sequence: MAKGDPKKPK GKMSAYAFFV QTCREEHKKK NPEVPVNFAE FSKKCSERWK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 91%, Horse: 100%, Human: 93%, Mouse: 86%, Pig: 82%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HMGB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HMGB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 200 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGB3

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Alternative Name: HMGB3

Background: The human HMG2a gene is transcribed mainly in the placenta. HMG2a encodes a protein which is part of the high mobility group (HMG) family. Members of this family are ubiquitously expressed and facilitate the formation of nucleoprotein complexes where the DNA is sharply bent.
Alias Symbols: HMG4, HMG-4, HMG2A, HMG-2a
Protein Interaction Partner: SDCBP, UBC, IPO9, DDX19A, UBXN1, MCTS1, SCRN1, PDIA4, PAPSS1, DENR, YWHAH, PAFAH1B1, GSS, ALDH7A1, ACAT2, HMGA1, CAND1, TFAP4, TERF2IP,
Protein Size: 200

Molecular Weight: 23 kDa

Gene ID: 3149

NCBI Accession: NM_005342, NP_005333

UniProt: O15347