TRPM3 antibody (N-Term)

Catalog No. ABIN183400

This Rabbit Polyclonal antibody specifically detects TRPM3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for TRPM3 antibody (N-Term) (ABIN183400)

Target: TRPM3 (Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRPM3 Antibody

Binding Specificity: N-Term

Purpose: TRPM3 Antibody - N-terminal region

Sequence: TPPVPVVVCD GSGRASDILA FGHKYSEEGG LINESLRDQL LVTIQKTFTY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TRPM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114292

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRPM3 antibody (ABIN183400)

Takumida, Ishibashi, Hamamoto, Hirakawa, Anniko: "Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear." in: Acta oto-laryngologica, Vol. 129, Issue 10, pp. 1050-60, (2011) (PubMed).

Target Details for TRPM3

Target: TRPM3 (Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3))

Alternative Name: TRPM3

Background:

Background Information: The product of the TRPM3 gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by TRPM3 mediates calcium entry, and this entry is potentiated by calcium store depletion.

Gene Name: Transient receptor potential cation channel, subfamily M, member 3

Alternative Symbols: GON-2, MLSN2, LTRPC3

Protein Name: TRPM3 protein EMBL AAH94699.1

Molecular Weight: 36kDa

Gene ID: 80036

UniProt: Q504Y1