TRIP13 antibody (C-Term)

Catalog No. ABIN183656

The Rabbit Polyclonal anti-TRIP13 antibody has been validated for WB and IHC. It is suitable to detect TRIP13 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit and Horse.

Quick Overview for TRIP13 antibody (C-Term) (ABIN183656)

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIP13 Antibody

Binding Specificity: C-Term

Sequence: LSGRVLRKLP FLAHALYVQA PTVTIEGFLQ ALSLAVDKQF EERKKLAAYI

Predicted Reactivity: Cow: 91%, Dog: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRIP13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRIP13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13

Background: The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
Alias Symbols: 16E1BP
Protein Interaction Partner: KRTAP26-1, KRTAP12-1, KRTAP12-2, MORN3, TEX37, METTL15, MGAT5B, C4orf33, GLYCTK, M1AP, LRR1, LNX1, RHOXF2, LOXL4, ZNF34, FNDC3B, TINAGL1, PBLD, SEMA4G, SPRYD7, PELI1, PLSCR3, PCMTD2, CYB5R2, AMDHD2, TNRC6A, DIP2A, DPYSL4, TRIP13, SIGLEC5, TPT1, SCP2, QARS
Protein Size: 432

Molecular Weight: 49 kDa

Gene ID: 9319

NCBI Accession: NM_004237, NP_004228

UniProt: Q15645