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Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) antibody

Antigen

Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18)
Synonyms AITR, GITR, GITR-D, TNFRSF18
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
1 reference available
Catalog no. ABIN184156
Quantity 50 µg  (Variants)
Price 317.90 $   Plus shipping costs $45.00
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) antibody

anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) antibody (2)

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name TNFRSF18 / GITR
Gene ID TNFRSF18
UniProt Q9Y5U5
Immunogen The immunogen for anti-TNFRSF18 antibody: synthetic peptide directed towards the C terminal of human TNFRSF18
Sequence LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAE EKGRLGDLWV
Cross-Reactivity Human
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-TNFRSF18 antibody concentration is 1 mg/ml.
Description The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Characteristics Antigen Size: 241 amino acids
Molecular Weight 26kDa

Application Details
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Application Notes WB Suggested Anti-TNFRSF18 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Hormones, Receptors, Growth Factors
Restrictions For Research Use only

Publications
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Product Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18)", type "Antibodies"
Hosts Rat (44), Rabbit (23), Mouse (13)
Reactivities Mouse (Murine) (54), Human (44), Rat (Rattus) (18)
Applications Flow Cytometry (FACS) (50), ELISA (29), Western Blotting (WB) (19), Immunofluorescence (IF) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (IHC) (1)
Conjugates PE (7), FITC (6), Biotin (5), RPE (2), APC (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (2), AA 26-161 (1)