Glial Cells Missing Homolog 1 (Drosophila) (GCM1) (C-Term) antibody

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Antigen
Synonyms GCM1, GCM, GCM-1, GCMA, hGCMa, GCMa, Gcm-rs2, Gcm1-rs1, glide, Gcma
Epitope
C-Term
(12), (6), (4), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human
(38), (18), (14), (1)
Host
Rabbit
(27), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(30), (15), (14), (11), (4), (4), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human GCM1
Sequence DFNSYVQSPA YHSPQEDPFL FTYASHPHQQ YSLPSKSSKW DFEEEMTYLG
Cross-Reactivity Dog (Canine), Human
Predicted Reactivity Human : 100 %, Horse : 90 %, Dog : 90 %, Rabbit : 80 %
Purification Affinity Purified
Alternative Name GCM1 / GCMA (GCM1 Antibody Abstract)
Background GCM1 is a DNA-binding protein with a gcm-motif (glial cell missing motif). GCM1 is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins.
Molecular Weight 49 kDa
NCBI Accession NP_003634, NM_003643
UniProt Q9NP62
Research Area Reproduction, Chromatin Binding Proteins, Transcription Factors
Application Notes WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 436 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C
Storage Comment Any unfrozen and/or unused material can be stored at 4 °C for short term use (< 1 week), and should not be re-frozen. For longer periods of storage, store at -24 °C
Supplier Images
Western Blotting (WB) image for anti-Glial Cells Missing Homolog 1 (Drosophila) (GCM1) (C-Term) antibody (ABIN184316) WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Western Blotting (WB) image for anti-Glial Cells Missing Homolog 1 (Drosophila) (GCM1) (C-Term) antibody (ABIN184316) WB Suggested Anti-GCM1
Antibody Titration: 0.2-1 µg/mL
Positive Control...
Background publications Chuang, Chang, Chang et al.: "Histone deacetylase 3 binds to and regulates the GCMa transcription factor." in: Nucleic acids research, Vol. 34, Issue 5, pp. 1459-69, 2006 (PubMed).

Catalog No. ABIN184316
$289.00
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