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Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibody

Details for Product No. ABIN184691, Supplier: Log in to see
Antigen
  • 3222402C23Rik
  • 9430073A21Rik
  • als2
  • ALS2CR6
  • Als2cr6
  • Alsin
  • ALSJ
  • IAHSP
  • mKIAA1563
  • PLSJ
  • si:dkey-33m14.1
Epitope
C-Term
21
5
4
3
3
2
2
2
2
1
1
1
Reactivity
Human
69
30
28
4
4
1
1
1
1
Host
Goat
46
18
9
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
43
30
24
12
11
5
2
2
Supplier
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Immunogen Peptide with sequence LKACYYQIQREKLN, from the C Terminus of the protein sequence according to NP_065970.2.
Blocking Peptide Blocking peptide for this product available: ABIN370347
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Alsin / ALS2 (ALS2 Antibody Abstract)
Background Synonyms: ALS2, amyotrophic lateral sclerosis 2 (juvenile), ALSJ, PLSJ, IAHSP, KIAA1563, ALS2CR6, FLJ31851, MGC87187, alsin
Gene ID 57679
NCBI Accession NP_065970
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: No signal obtained yet but low background observed in Human Brain extracts at upto 1 µg/mL.
IHC: In paraffin embedded Human Cortex shows pixulate cytoplasm staining in some neuronal cells. Recommended concentration: 3-5 µg/mL.
Restrictions For Research Use only
Format Liquid
Concentration 100µg specific antibody in 200µl
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Yang, Hentati, Deng, Dabbagh, Sasaki, Hirano, Hung, Ouahchi, Yan, Azim, Cole, Gascon, Yagmour, Ben-Hamida, Pericak-Vance, Hentati, Siddique: "The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis." in: Nature genetics, Vol. 29, Issue 2, pp. 160-5, 2001 (PubMed).