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Quinone Reductase 1 (NQO1) antibody
| Antigen | Quinone Reductase 1 (NQO1) |
| Synonyms | DTD, QR1, DHQU, DIA4, NMOR1, NMORI, Dtd, Ox1, Qr1, Dia4, Nmo1, Ox-1, Nmo-1, Nmor1, AV001255, MGC93075 |
| Clonality | Polyclonal |
| Host |
Alternatives Goat |
| Reactivity |
Alternatives Human |
| Application |
Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
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5 references available |
| Catalog no. | ABIN184714 |
| Quantity | 100 ug (Variants) |
| Price | 501.80 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | NQO1 (Quinone reductase 1) |
| Gene ID | 1728, 18104 (mouse) |
| Immunogen | C-SIPTDNQIKARK |
| Format | Affinity-purified |
| Description | All names and symbols: NQO1, NAD(P)H dehydrogenase, quinone 1, DTD, QR1, DHQU, DIA4, NMOR1, NMORI, diaphorase-4, diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), NAD(P)H:menadione oxidoreductase 1, dioxin-inducible 1. Official Symbol: NQO1. RefSeq number(s): NP_000894.1, NP_001020604.1, NP_001020605.1. Gene ontology terms: NAD(P)H dehydrogenase (quinone) activity, cytochrome b5 reductase activity, nitric oxide biosynthesis, response to toxin, synaptic transmission, cholinergic, xenobiotic metabolism, electron transport, cytoplasm, oxidoreductase activity |
| Specificity | This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1). Human, Mouse, Rat 274 aa |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx. 30kDa band observed in Human Kidney and Lung lysates (calculated MW of 30.9kDa according to NP_000894.1). Recommended concentration: 0.03-0.1µg/ml. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Research Area | Metabolism, Drugs |
| Restrictions | For Research Use only |
Images
| ABIN184714 staining (0.03µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. |
Publications
| Publications |
Asher, Lotem, Kama et al.: "NQO1 stabilizes p53 through a distinct pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 5, pp. 3099-104, 2002 (PubMed).
van Horssen, Schreibelt, Boe et al.: "NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions." in: Free radical biology & medicine, Vol. 41, Issue 2, pp. 311-7, 2006 (PubMed). Ritz, Wan, Diaz-Sanchez: "Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L33-9, 2007 (PubMed). Tanaka, Aleksunes, Cui et al.: "ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 108, Issue 2, pp. 247-57, 2009 (PubMed). Schriner, Avanesian, Liu et al.: "Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses." in: Free radical biology & medicine, Vol. 47, Issue 5, pp. 577-84, 2009 (PubMed). |
Alternatives
Alternatives for antigen "Quinone Reductase 1 (NQO1)", type "Antibodies"
| Hosts | Rabbit (32), Mouse (23), Goat (6) |
| Reactivities | Human (56), Rat (Rattus) (26), Mouse (Murine) (24), Pig (Porcine) (20), Rabbit (18), Guinea Pig (15), Horse (Equine) (15), Cow (Bovine) (3), Dog (Canine) (3), Fruit Fly (Drosophila melanogaster) (3), Monkey (1) |
| Applications | Western Blotting (WB) (43), Immunofluorescence (IF) (30), Immunoprecipitation (IP) (21), Flow Cytometry (FACS) (20), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), ELISA (6), Enzyme Immunoassay (EIA) (5), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1) |
| Conjugates | HRP (4), Biotin (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | C-Term (5), Center (1) |




Alternatives