SHOW MY LAST SEARCH SHOW TUTORIAL VIDEOShow Search Tutorial Video
(requires Flash, opens in new window) Show Tutorial VideoShow Search Tutorial Video
(requires Flash, opens in new window)
Product Details

anti-quinone reductase 1 (NQO1) antibody

Overview

Image for anti-quinone reductase 1 (NQO1) antibody
Antigen: Quinone reductase 1 (NQO1)
Clonality: Polyclonal
Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
Reactivity: Human
Host: Goat
5 references available 5 references available
Quantity: 100 ug
Price: 337,68 $   (Plus shipping costs and VAT, Invoice in EUR)
Order number: ABIN184714
Availability: Ships within 5 Business days
Hints on ordering Hints on ordering
Add to basket

on this page

Additional Information
Application Details
Publications
Images
Related Products
Protocols

Customer Service

Technical Inquiry
Send product details to colleague
Download Datasheet

Additional Information  » anti-quinone reductase 1 (NQO1) antibody

back to top ^


Antigen Quinone reductase 1 (NQO1)
Gene ID 1728 , 18104 (mouse)
Immunogen C-SIPTDNQIKARK
Reactivity Human
Clonality Polyclonal
Format Affinitiy-purified
Description All names and symbols: NQO1, NAD(P)H dehydrogenase, quinone 1, DTD, QR1, DHQU, DIA4, NMOR1, NMORI, diaphorase-4, diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), NAD(P)H:menadione oxidoreductase 1, dioxin-inducible 1. Official Symbol: NQO1. RefSeq number(s): NP_000894.1, NP_001020604.1, NP_001020605.1. Gene ontology terms: NAD(P)H dehydrogenase (quinone) activity, cytochrome b5 reductase activity, nitric oxide biosynthesis, response to toxin, synaptic transmission, cholinergic, xenobiotic metabolism, electron transport, cytoplasm, oxidoreductase activity
Host Goat
Specificity This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1). Human, Mouse, Rat 274 aa

Application Details  » anti-quinone reductase 1 (NQO1) antibody

back to top ^


Application ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
» Click here to view 4 available protocols!
Application Notes Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx. 30kDa band observed in Human Kidney and Lung lysates (calculated MW of 30.9kDa according to NP_000894.1). Recommended concentration: 0.03-0.1µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Metabolism, Drugs
Restrictions For Research Use only

Publications  » anti-quinone reductase 1 (NQO1) antibody

back to top ^


Publications Asher, Lotem, Kama et al.: "NQO1 stabilizes p53 through a distinct pathway." In: Proceedings of the National Academy of Sciences of the United States of America , Vol. 99, Issue 5, pp. 3099-104, 2002 (PubMed)

van Horssen, Schreibelt, Boe et al.: "NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions." In: Free radical biology & medicine , Vol. 41, Issue 2, pp. 311-7, 2006 (PubMed)

Ritz, Wan, Diaz-Sanchez: "Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract." In: American journal of physiology. Lung cellular and molecular physiology , Vol. 292, Issue 1, pp. L33-9, 2007 (PubMed)

Tanaka, Aleksunes, Cui et al.: "ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling." In: Toxicological sciences : an official journal of the Society of Toxicology , Vol. 108, Issue 2, pp. 247-57, 2009 (PubMed)

Schriner, Avanesian, Liu et al.: "Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses." In: Free radical biology & medicine , Vol. 47, Issue 5, pp. 577-84, 2009 (PubMed)