COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) antibody

Antigen: COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2)

Synonyms: csn2, COPS2, MGC137288, Tb03.48O8.600, CSN2, SGN2, ALIEN, TRIP15, Trip15, zgc:86624, wu:fc05f05, wu:fc06g10, wu:fc60f04, wu:fl94f12

Clonality: Polyclonal

Host: Goat

Reactivity: Human, Mouse (Murine)

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN184997

Additional Information

Alternative name: CSN2 / TRIP15

Gene ID: 9318, 12848 (mouse), 261736 (rat)

Immunogen: Peptide with sequence C-LNSLNQAVVSKLA, from the C Terminus of the protein sequence according to NP_004227.1, NP_001137359.1

Format: Affinity-purified

Description: All names and symbols: COPS2, TRIP15, COPS2, CSN2, thyroid receptor interacting protein 15, SGN2, COP9 constitutive photomorphogenic homolog subunit 2, thyroid receptor interacting protein 15, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9, subunit 2, ALIEN, COP9 signalosome complex subunit 2, JAB1-containing signalosome subunit 2. Official Symbol: COPS2. RefSeq number(s): NP_004227.1, NP_001137359.1. Gene ontology terms: protein binding, signal transducer activity, signal transduction, transcription from Pol II promoter, cytoplasm, signalosome complex.

Specificity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 48kDa band observed in Human Brain, Mouse Brain lysates and in lysates of Mouse putuitary cell line NIH3T3 (calculated MW of 51.6kDa according to NP_004227.1). Recommended concentration: 1-3µg/ml. Immunohistochemistry: In paraffin embedded Human Thyroid Gland shows nclear and cytoplasm staining in activated epithelial cells Recommended concentration, 3-5µg/ml.

Concentration: 100µg specific antibody in 200µl

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: For long-term storage keep aliquots at -20°C. (Store no longer than 12 months at 4°C). Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Escher, Kob, Tenbaum et al.: "Various members of the E2F transcription factor family interact in vivo with the corepressor alien." in: Journal of proteome research, Vol. 6, Issue 3, pp. 1158-64, 2007 (PubMed).