Fibroblast Growth Factor Receptor 1 (FGFR1) antibody

Antigen: Fibroblast Growth Factor Receptor 1 (FGFR1)

Synonyms: FGFR, fgfr, fgfr1-A, XFGFRA2, CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR, N-SAM, FLJ99988, Flt-2, Fgfr-1, AW208770, fgfr1, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, DFR1, DFR1/DFGF-R2, DPR3, DTRK(FR1), DmHD-38, Dtk1, EMS2, FGF-R2, FGFR2, FR1, HD-38, HTL/FGFR1, Htl, Tk1, i100, i150, i79, j372, DmelCG7223, CG7223, FGFR1, FLG-1, cek, flg, flt2, kal2, bfgfr, cd331, fgfbr, flt-2, hbgfr, n-sam, X1FGFR, xfgfr1, XFGFR-1, MGC80912

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185351

Additional Information

Alternative name: FGFR1

Gene ID: 2260

Immunogen: CLPRHPAQLANGGLKR

Format: Affinity-purified

Description: All names and symbols: FGFR1, H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), FLG protein, N-sam tyrosine kinase, tyrosylprotein kinase, protein-tyrosine kinase, FMS-like tyrosine kinase 2, hydroxyaryl-protein kinase, fms-related tyrosine kinase-2, heparin-binding growth factor receptor, basic fibroblast growth factor receptor 1. Official Symbol: FGFR1. RefSeq number(s): NP_000595, NP_056934, NP_075593, NP_075594, NP_075599. Gene ontology terms: ATP binding, MAPKKK cascade, fibroblast growth factor receptor activity, fibroblast growth factor receptor signaling pathway, heparin binding, integral to plasma membrane, protein amino acid phosphorylation, protein amino acid phosphorylation, protein serine/threonine kinase activity, protein-tyrosine kinase activity, protein-tyrosine kinase activity, receptor activity, skeletal development, transferase activity

Specificity: This antibody is expected to recognise 5 (out of nine reported) isoforms (as represented by NP_000595, NP_056934, NP_075593, NP_075594, NP_075599). Human, Dog, Chimpanzee 822 aa, 820 aa, 733 aa, 731 aa, 302 aa, 300 aa, 662 aa, 150 aa, 785 aa

Synonyms: FGFR, fgfr, fgfr1-A, XFGFRA2, CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR, N-SAM, FLJ99988, Flt-2, Fgfr-1, AW208770, fgfr1, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, DFR1, DFR1/DFGF-R2, DPR3, DTRK(FR1), DmHD-38, Dtk1, EMS2, FGF-R2, FGFR2, FR1, HD-38, HTL/FGFR1, Htl, Tk1, i100, i150, i79, j372, DmelCG7223, CG7223, FGFR1, FLG-1, cek, flg, flt2, kal2, bfgfr, cd331, fgfbr, flt-2, hbgfr, n-sam, X1FGFR, xfgfr1, XFGFR-1, MGC80912

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 75kDa band observed in human breast lysates (calculated MW of 82.2kDa according to NP_075593, 81.9kDa according to NP_075594). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Cancer, Growth Factors, Tyrosine Kinases, Angiogenesis, Cytokines, Receptors

Restrictions: For Research Use only

Images

ABIN185351 (0.3µg/ml) staining of human breast lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Torry, Mukherjea, Arroyo et al.: "Expression and function of placenta growth factor: implications for abnormal placentation." in: Journal of the Society for Gynecologic Investigation, Vol. 10, Issue 4, pp. 178-88, 2003 (PubMed).